Article
Gut Microbiota Composition Modulates the Magnitude and Quality of Germinal Centers during Plasmodium Infections
1 Dec 2020
Abstract excerpt
Gut microbiota composition is associated with human and rodent Plasmodium infections, yet the mechanism by which gut microbiota affects the severity of malaria remains unknown. Humoral immunity is critical in mediating the clearance of Plasmodium blood stage infections, prompting the hypothesis that mice with gut microbiota-dependent decreases in parasite burden exhibit better germinal center (GC) responses. In...
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