Back to search

Article

<i>HMGA1</i> zebrafish co-orthologue hmga1b can modulate p53-dependent cellular responses but is unable to control the alternative splicing of <i>psen1</i>

2018-01-02

Abstract excerpt

<h4>ABSTRACT</h4> The HIGH MOBILITY GROUP AT-HOOK 1 (HMGA1) family of chromatin-binding proteins plays important roles in cellular responses to low oxygen. HMGA1 proteins regulate gene activity both in the nucleus and within mitochondria. They are expressed mainly during embryogenesis and their upregulation in cancerous cells indicates poor prognosis. The human HMGA1a isoform is upregulated under hypoxia via oxid...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8ac5e3ef-dc7f-5844-ba2d-4dde7480c83c
DOI
10.1101/241927
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
<i>HMGA1</i> zebrafish co-orthologue hmga1b can modulate p53-dependent cellular responses but is unable to control the alternative splicing of <i>psen1</i>DOI 10.1101/241927
HMGI(Y) and HMGI-C DysregulationSemantic proximity
Cellular carcinogenesis in preleukemic conditions:drivers and defenses.Semantic proximity
Multiple functions of HMGB1 in cancerSemantic proximity
HMGA1 in cancer: Cancer classification by locationSemantic proximity
High Mobility Group Box 1 (HMGB1): Molecular Signaling and Potential Therapeutic StrategiesSemantic proximity
Role of HMGB1 and its associated signaling pathways in human malignanciesSemantic proximity
p53/HMGB1 Complexes Regulate Autophagy and ApoptosisSemantic proximity
Chromosomal Translocations in Benign Tumors:<i>The HMGI Proteins</i>Semantic proximity
HMGB1: The jack‐of‐all‐trades protein is a master DNA repair mechanicSemantic proximity
Multi-omics Analysis of Dsup Expressing Human Cells Reveals Open Chromatin Architectural Dynamics Underyling RadioprotectionSemantic proximity
IDH1 and IDH2: Not Your Typical OncogenesSemantic proximity
Dysregulated expression of <i>Hoxa1</i> isoforms in hematopoietic stem and progenitor cells causes myelodysplastic syndromesSemantic proximity
Select a neighboring publication to make it the new centre.