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Activated Human Pancreatic Stellate Cells Signature Communication in Type 1 Diabetes

2026-02-04

Abstract excerpt

<title>Abstract</title> <p>Background Type 1 diabetes (T1D) is an autoimmune disease resulting in the destruction of pancreatic β-cells leading to insulin deficiency and hyperglycemia. Single cell transcriptomic analysis of human islets demonstrated profound β-cell changes and revealed heterogeneity in endocrine and exocrine cells in T1D. Pancreatic stellate cells (PSCs), the resident mesenchymal cells of the pa...

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Literature Corpus work
8ab1fe92-c90a-5044-8235-b5951aa7ef3a
DOI
10.21203/rs.3.rs-8704281/v1
Open publication

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Activated Human Pancreatic Stellate Cells Signature Communication in Type 1 DiabetesDOI 10.21203/rs.3.rs-8704281/v1
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