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Article

Overview of Chikungunya Virus Pathogenesis, Genome Variation, Epidemiology, and Control.

Virus research - 1 Apr 2026

Hamrahjoo Morvarid, Shams Faezeh, Saadat Nastaran, Marhamati Shayan, Teimoori Ali

Abstract excerpt

Chikungunya virus (CHIKV) is an arthropod-borne alphavirus that causes an abrupt febrile illness typically marked by intense arthralgia, rash, and profound fatigue. Following transmission predominantly through Aedes mosquitoes, the virus is able to infect a broad range of host cell types, such as fibroblasts and macrophages, resulting in acute viremia with high viral titers and, in a subset of patients, prolonged...

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Identifiers

PMID: 41722616
DOI: 10.1016/j.virusres.2026.199703
PMCID: PMC12964048

Genes

MXRA8

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