Article

EP4 as a Therapeutic Target for Aggressive Human Breast Cancer

2018-02-13

Abstract excerpt

G protein-coupled receptors (GPCRs, also called seven-transmembrane or heptahelical receptors) are a superfamily of cell surface receptor proteins that bind to many extracellular ligands and transmit signals to an intracellular guanine nucleotide-binding protein (G protein). When a ligand binds, the receptor activates the attached G-protein by causing the exchange of Guanosine-5'-triphosphate (GTP) for guanos...

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Literature Corpus work: 8a8e545b-0562-540a-8a21-239e52547146
DOI: 10.20944/preprints201802.0095.v1

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