Article
Chromatin tethering of incoming foamy virus by the structural Gag protein.
Traffic (Copenhagen, Denmark) - 1 Sept 2008
Tobaly-Tapiero Joelle, Bittoun Patricia, Lehmann-Che Jacqueline, Delelis Olivier, Giron Marie-Lou, de Thé Hugues, Saïb Ali
Abstract excerpt
Retroviruses hijack cellular machineries to productively infect their hosts. During the early stages of viral replication, proviral integration relies on specific interactions between components of the preintegration complex and host chromatin-bound proteins. Here, analyzing the fate of incoming primate foamy virus, we identify a short domain within the C-terminus of the structural Gag protein that efficiently...
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