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The prefusion structure of the HERV-K (HML-2) Env spike complex

2025-03-19

Abstract excerpt

The human endogenous retrovirus K (HERV-K) is a retrovirus that got assimilated into the human genome in ancient times and has been inherited in our germline ever since. It enters cells using a class-I spike protein (Env) that mediates receptor recognition and membrane fusion. On top of having a biological role during development, HERV-K is activated in amyotrophic lateral sclerosis, various cancers, and other pat...

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Literature Corpus work
751f4f79-5e15-5e90-82e5-0045bfd76996
DOI
10.1101/2025.03.19.644160
Open publication

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The prefusion structure of the HERV-K (HML-2) Env spike complexDOI 10.1101/2025.03.19.644160
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