Article

Functional and antigenic constraints on the Nipah virus fusion protein

2025-10-15

Abstract excerpt

Nipah virus is a highly pathogenic virus in the family Paramyxoviridae that utilizes two distinct surface glycoproteins to infect cells. The receptor-binding protein (RBP) binds host receptors whereas the fusion protein (F) merges viral and host membranes. Here, we use non-replicative pseudoviruses to safely measure the effects of all F single amino-acid residue mutations on its cell entry function and neutraliza...

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Literature Corpus work: 14cd6207-6073-56b3-97de-5b1ee9c6908a
DOI: 10.1101/2025.10.15.682664

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