Article

PseudoCell: A Multi-Valued Logical Regulatory Network to Investigate Premature Senescence Dynamics and Heterogeneity

2023-07-22

Abstract excerpt

<h4>ABSTRACT</h4> Premature cellular senescence is a pivotal process in aging and age-related diseases, triggered by various stressors. However, this is not a homogeneous phenotype, but a heterogeneous cellular state composed of multiple senescence programs with different compositions. Therefore, understanding the complex dynamics of senescence programs requires a systemic approach. We introduce PseudoCell, a mul...

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Literature Corpus work: 8a2a0a9f-abce-5cf8-9f08-bc5e3c234251
DOI: 10.1101/2023.07.20.549793

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