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Decoding senescence of aging single cells at the nexus of biomaterials, microfluidics, and spatial omics

26 Nov 2024

Abstract excerpt

Aging has profound effects on the body, most notably an increase in the prevalence of several diseases. An important aging hallmark is the presence of senescent cells that no longer multiply nor die off properly. Another characteristic is an altered immune system that fails to properly self-surveil. In this multi-player aging process, cellular senescence induces a change in the secretory phenotype, known as...

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PMID: 39592596
DOI: 10.1038/s41514-024-00178-w

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