Article

Immunogenicity of a public neoantigen derived from mutated <i>PIK3CA</i>

2021-04-09

Abstract excerpt

<h4>ABSTRACT</h4> Public neoantigens (NeoAgs) represent an elite class of shared cancer-specific epitopes derived from recurrent mutations in driver genes that are restricted by prevalent HLA alleles. Here, we report on a high-throughput platform combining single-cell transcriptomic and T cell receptor (TCR) sequencing to establish whether mutant (Mut) PIK3CA , among the most common genomically altered driver on...

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Literature Corpus work: 8a0fb4c6-473e-50ed-849d-9a2daab8aff4
DOI: 10.1101/2021.04.08.439061

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