Article

Revisiting the regulation of the capsular polysaccharide biosynthesis gene cluster in <i>Staphylococcus aureus</i>

2019-04-24

Abstract excerpt

In Staphylococcus aureus , the capsular polysaccharide (CP) protects against phagocytosis, but also hinders adherence to endothelial cells and matrix proteins. Its biosynthesis is tightly controlled resulting in a heterogeneous phenotype within a population and CP being mainly detectable in non-growing cells. Capsular biosynthesis genes are encoded by a conserved capA-P operon whose expression is driven by an up...

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Literature Corpus work: 8a0677b6-921f-5148-8f03-1afde16aa41c
DOI: 10.1101/614925

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