Article
Functional organization of the gene cluster involved in the synthesis of the pneumococcal capsule.
International microbiology : the official journal of the Spanish Society for Microbiology - 1 Sept 1999
García E, Llull D, López R
Abstract excerpt
Streptococcus pneumoniae is a major human pathogen and its capsular polysaccharide has been shown to be the main virulence factor. The molecular organization of the genes governing the formation of this capsule was not studied until the 1990s. The capsular clusters (cap) of eight of the 90 known pneumococcal types have now been studied. The cap operon, located between the dexB and aliA genes, is arranged as a...
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