Article

H3K9 methyltransferase EHMT2/G9a controls ERVK-driven non-canonical imprinted genes

2021-03-31

Abstract excerpt

Unlike regular imprinted genes, non-canonical imprinted genes are known to not depend on gamete-specific DNA methylation difference. Instead, the paternal allele-specific expression of these genes in the extra-embryonic lineages depends on an H3K27me3-based imprint in the oocyte, but this marking is not maintained beyond pre-implantation development. The maintenance of non-canonical imprinting corresponds to mater...

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Literature Corpus work: 89f0a756-6c22-5d54-804b-d74af13ca123
DOI: 10.1101/2021.03.29.437617

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