Article

Revealing cancer driver genes through integrative transcriptomic and epigenomic analyses with Moonlight

2024-03-15

Abstract excerpt

Cancer involves dynamic changes caused by (epi)genetic alterations such as mutations or abnormal DNA methylation patterns which occur in cancer driver genes. These driver genes are divided into oncogenes and tumor suppressors depending on their function and mechanism of action. Discovering driver genes in different cancer (sub)types is important not only for increasing current understanding of carcinogenesis but a...

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Literature Corpus work: 8982472b-cf80-57e7-8fd4-c6309fb0dfa2
DOI: 10.1101/2024.03.14.584946

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