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Chimeric Antigen Receptor (CAR) T Cells: A Detailed Review of Origins, Engineering, and Therapeutic Impact

2025-08-11

Abstract excerpt

CAR T cell therapy is a groundbreaking immunotherapeutic approach that harnesses genetically engineered T cells to target and destroy cancer cells with specificity and potency. Emerging from decades of immunological and genetic engineering advances, CAR T cells represent a paradigm shift in cancer treatment, especially for hematologic malignancies refractory to conventional therapies. This review provides an in-de...

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Literature Corpus work
89589153-c7f0-5a99-9619-c8df8f4a45b7
DOI
10.22541/au.175494696.62742704/v1
Open publication

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