Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Chimeric Antigen Receptor T-cell Therapy to Target Hematologic Malignancies

5 Nov 2014

Abstract excerpt

Several decades of humoral immunotherapy using monoclonal antibodies and cellular immunotherapy using hematopoietic cell transplantation have recently culminated in a successful merger: the development and clinical application of genetically engineered antibody-T cell chimeras. Also known as chimeric antigen receptor T cells (CAR T cells), these entities combine the exquisite antigen specificity of antibodies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Nanowire Synthesis and Applications
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25371415
DOI: 10.1158/0008-5472.can-14-1530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Chimeric Antigen Receptor T-cell Therapy to Target Hematologic MalignanciesPMID 25371415Read ↗

Chimeric Antigen Receptor (CAR) T Cells: A Detailed Review of Origins, Engineering, and Therapeutic ImpactSemantic proximity Read ↗

Chimeric Antigen Receptors: A Paradigm Shift in ImmunotherapySemantic proximity Read ↗

Chimeric antigen receptor-modified T cells strike backSemantic proximity Read ↗

Engineering and Design of Chimeric Antigen ReceptorsSemantic proximity Read ↗

Emerging Cellular Therapies for CancerSemantic proximity Read ↗

Engineering chimeric antigen receptor-T cells for cancer treatment.Semantic proximity Read ↗

Chimeric antigen receptor for adoptive immunotherapy of cancer: latest research and future prospectsSemantic proximity Read ↗

Current and future concepts for the generation and application of genetically engineered CAR-T and TCR-T cellsSemantic proximity Read ↗

Chimeric Antigen Receptors Modified T-Cells for Cancer TherapySemantic proximity Read ↗

Chimeric Antigen Receptor T-Cell Therapy: What We Expect SoonSemantic proximity Read ↗

From molecular design to clinical translation: dual-targeted CAR-T strategies in cancer immunotherapySemantic proximity Read ↗

T cell receptor‐based cancer immunotherapy: Emerging efficacy and pathways of resistanceSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.