Article

Astral microtubule crosslinking safeguards uniform nuclear distribution in the <i>Drosophila</i> syncytium

2019-11-29

Abstract excerpt

The early insect embryo develops as a multinucleated cell distributing the genome uniformly to the cell cortex. Mechanistic insight for nuclear positioning beyond cytoskeletal requirements is missing. Contemporary hypotheses propose actomyosin driven cytoplasmic movement transporting nuclei, or repulsion of neighbor nuclei driven by microtubule motors. Here, we show that microtubule crosslinking by Feo and Klp3A i...

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Identifiers and source

Literature Corpus work: 89504849-1095-5eb7-9472-3818782be4b8
DOI: 10.1101/859975

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