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Pathological Features of Echovirus-11-Associated Brain Damage in Mice Based on RNA-Seq Analysis

10 Dec 2021

Abstract excerpt

Echovirus 11 (E11) is a neurotropic virus that occasionally causes fatal neurological diseases in infected children. However, the molecular mechanism underlying the disease and pathological spectrum of E11 infection remains unclear. Therefore, we modelled E11 infection in 2-day-old type I interferon receptor knockout (IFNAR-/-) mice, which are susceptible to enteroviruses, with E11, and identified symptoms...

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PMID: 34960747
DOI: 10.3390/v13122477

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