Article

Pangenome discovery and characterization of human protein-coding duplicated genes

2026-08-06

Abstract excerpt

<h4>ABSTRACT</h4> Protein-coding genes mapping to high-identity segmental duplications (SDs) have been difficult to annotate and characterize and are the source of most previously unknown protein-coding genes being discovered as part of the human pangenome. Here, we combine long-read assembled human genomes (298) and long-read transcriptome data (5.6 billion full-length cDNA from 83 tissues) to phylogenetically i...

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Literature Corpus work: 892e8e20-9694-5302-84df-57fdee8d35ac
DOI: 10.64898/2026.08.05.743125

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