Article

Widespread Regulatory Turnover Across Human Segmental Duplications

2026-01-22

Abstract excerpt

Segmental duplications (SDs) are a pervasive feature of eukaryotic genomes, enabling genomic innovation via the duplication of genes and cis -regulatory elements. However, the regulatory mechanisms that govern these regions of the genome after duplication are not well understood. The repetitive nature of SDs pose problems for short-read assays such as ChIP-seq and DNase-seq as they create reads that map to more t...

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Literature Corpus work: 75f1027b-97f0-5f08-bae7-60312aa53d5a
DOI: 10.64898/2026.01.21.700947

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