Article

Model-based analysis of polymorphisms in an enhancer reveals cis-regulatory mechanisms

2020-02-09

Abstract excerpt

<h4>ABSTRACT</h4> It is challenging to predict the impact of small genetic changes such as single nucleotide polymorphisms on gene expression, since mechanisms involved in gene regulation and their cis-regulatory encoding are not well-understood. Recent studies have attempted to predict the functional impact of non-coding variants based on available knowledge of cis-regulatory encoding, e.g., transcription factor...

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Literature Corpus work: 89193961-24ba-591c-bab7-fe49a19db3f1
DOI: 10.1101/2020.02.07.939264

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