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A spatially anchored transcriptomic atlas of the human kidney papilla identifies significant immune injury in patients with stone disease

19 Jul 2023

Abstract excerpt

Kidney stone disease causes significant morbidity and increases health care utilization. In this work, we decipher the cellular and molecular niche of the human renal papilla in patients with calcium oxalate (CaOx) stone disease and healthy subjects. In addition to identifying cell types important in papillary physiology, we characterize collecting duct cell subtypes and an undifferentiated epithelial cell type...

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PMID: 37468493
DOI: 10.1038/s41467-023-38975-8

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