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Article

Efficacy and functionality of lipoprotein OprI from Pseudomonas aeruginosa as adjuvant for a subunit vaccine against classical swine fever.

Vaccine - 29 May 2006

Rau Henriette, Revets Hilde, Cornelis Pierre, Titzmann Anja, Ruggli Nicolas, McCullough Kenneth C, Summerfield Artur

Abstract excerpt

Bacterial lipoproteins are potent stimulators of innate immune responses and can mediate humoral and cytotoxic T cell responses without additional adjuvants. OprI derived from Pseudomonas aeruginosa was tested in vitro and in vivo for its adjuvant potential in the context of a classical swine fever (CSF) subunit vaccine. OprI activated porcine monocyte-derived dendritic cells (MoDC), upregulating CD80/86 and MHC...

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Share to Adjuvants, Immunologic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Classical Swine Fever Virus

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Source

Identifiers

PMID: 16678311
DOI: 10.1016/j.vaccine.2006.03.028

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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