Article

Glycoprotein-glycoprotein receptor binding detection using bioluminescence resonance energy transfer (BRET)

2023-01-21

Abstract excerpt

The glycoprotein receptors, members of the large G protein-coupled receptors (GPCRs) family, are characterized by a large extracellular domains responsible of binding their glycoprotein hormones. Hormone-receptor interactions are traditionally analyzed by ligand-binding assays most often using radiolabeling but also by thermal shift assays. However, the use of radioisotopes requires appropriate laboratory conditio...

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Identifiers and source

Literature Corpus work: 889aa262-c1a1-5507-b276-6b74d5199e27
DOI: 10.1101/2023.01.21.525003

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