Article

Human RIG-I deficiency confers susceptibility to Kaposi Sarcoma via loss of latency control

2025-09-20

Abstract excerpt

Kaposi sarcoma (KS), caused by the DNA-virus Kaposi's sarcoma-associated herpesvirus (KSHV), occurs during T cell immunosuppression (HIV, transplant) or sporadically in some 'immunocompetent' and aging individuals (endemic, classic KS respectively). In absence of known T cell immunosuppression KS pathogenesis remains enigmatic. KS therapy with topical or oral retinoid medication, or recombinant alpha interferon, c...

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Literature Corpus work: 88759a04-a9d8-5bb2-936c-87771a80a4f8
DOI: 10.1101/2025.09.19.676307

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