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Article

RIG-I Detects Kaposi’s Sarcoma-Associated Herpesvirus Transcripts in a RNA Polymerase III-Independent Manner

9 Jul 2018

Abstract excerpt

ABSTRACT Retinoic acid-inducible gene I (RIG-I) is a cytosolic pathogen recognition receptor that initiates the innate immune response against many RNA viruses. We previously showed that RIG-I restricts Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation (J. A. West et al., J Virol 88:5778–5787, 2014, https://doi.org/10.1128/JVI.03226-13 ). In this study, we report that KSHV stimulates the RIG-I signaling...

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Identifiers

PMID: 29970461
DOI: 10.1128/mbio.00823-18

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