Article
A Viral-Encoded Homologue of IPS-1 Modulates Innate Immune Signaling During KSHV Lytic Replication
2024-07-25
Abstract excerpt
<h4>ABSTRACT</h4> Modulation of innate immunity is critical for virus persistence in a host. In particular, viral-encoded disruption of type I interferon, a major antiviral cytokine induced to fight viral infection, is a key component in the repertoire of viral pathogenicity genes. We have identified a previously undescribed open reading frame within the Kaposi’s sarcoma-associated herpesvirus (KSHV) genome that...
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Identifiers and source
- Literature Corpus work
- 217dcfc4-75fe-5076-ac5c-c3035ddfc4a2
- DOI
- 10.1101/2024.07.24.604690
