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Article

An Update on Autoinflammatory Diseases: Interferonopathies.

Current rheumatology reports - 30 May 2018

Davidson Sophia, Steiner Annemarie, Harapas Cassandra R, Masters Seth L

Abstract excerpt

PURPOSE OF REVIEW: Type I interferons (IFNαβ) induce the expression of hundreds of genes; thus, it is unsurprising that the initiation, transmission, and resolution of the IFNαβ-mediated immune response is tightly controlled. Mutations that alter nucleic acid processing and recognition, ablate IFNαβ-specific negative feedback mechanisms, or result in dysfunction of the proteasome system can all induce pathogenic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29846818
DOI: 10.1007/s11926-018-0748-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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