Article

Viroporin activity from rotavirus nonstructural protein 4 induces intercellular calcium waves that contribute to pathogenesis

2024-05-07

Abstract excerpt

Acute gastroenteritis remains the second leading cause of death among children under the age of 5 worldwide. While enteric viruses are the most common etiology, the drivers of their virulence remain incompletely understood. We recently found that cells infected with rotavirus, the most prevalent enteric virus in infants and young children, initiate hundreds of intercellular calcium waves that enhance both fluid se...

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Literature Corpus work: 8857fe9a-cafc-5d44-8e57-d34f753950e5
DOI: 10.1101/2024.05.07.592929

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