Article

Purinergic Signaling Drives Multiple Aspects of Rotavirus Pathophysiology

2024-05-07

Abstract excerpt

Rotavirus causes life-threatening diarrhea in children, resulting in ∼200,000 deaths/year. The current treatment during infection is Oral Rehydration Solution which successfully replenishes fluids but does not alleviate diarrhea volume or severity. As a result, there is an urgent need to better understand rotavirus pathophysiology and develop more effective pediatric therapeutics. Rotavirus primarily infects the t...

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Literature Corpus work: 22ffa535-e7ac-5d9d-a369-5064b9639722
DOI: 10.1101/2024.05.07.592953

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