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Rotavirus NSP1 contributes to intestinal viral replication, pathogenesis, and transmission

2021-06-18

Abstract excerpt

<h4>ABSTRACT</h4> Rotavirus (RV)-encoded non-structural protein 1 (NSP1), the product of gene segment 5, effectively antagonizes host interferon (IFN) signaling via multiple mechanisms. Recent studies with the newly established RV reverse genetics system indicate that NSP1 is not essential for the replication of simian RV SA11 strain in cell culture. However, the role of NSP1 in RV infection in vivo remains poor...

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Literature Corpus work
5d43baa5-cf30-55d3-b4da-f80a4a40c469
DOI
10.1101/2021.06.17.448915
Open publication

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Rotavirus NSP1 contributes to intestinal viral replication, pathogenesis, and transmissionDOI 10.1101/2021.06.17.448915
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