Article

Application of a mathematical model to prevent in vivo amplification of antibiotic-resistant bacterial populations during therapy

2003-07-15

Abstract excerpt

The worldwide increase in the prevalence of multi-antibiotic–resistant bacteria has threatened the physician’s ability to provide appropriate therapy for infections. The relationship between antimicrobial drug concentration and infecting pathogen population reduction is of primary interest. Using data derived from mice infected with the bacterium Pseudomonas aeruginosa and treated with a fluoroquinolone antibiotic...

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Identifiers and source

Literature Corpus work: 882c4dee-bb61-5e27-b883-cc64ac4d34ba
DOI: 10.1172/jci200316814

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