Article
Immune cell infiltration characteristics and related core genes in lupus nephritis: results from bioinformatic analysis
2019-09-24
Abstract excerpt
<title>Abstract</title> <p>Background Lupus nephritis (LN) is a common complication of systemic lupus erythematosus that presents a high risk of end-stage renal disease. In the present study, we used CIBERSORT and gene set enrichment analysis (GSEA) of gene expression profiles to identify immune cell infiltration characteristics and related core genes in LN. Results Datasets from the Gene Expression Omnibus, GSE3...
Topics
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- Atherosclerosis and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Chronic Kidney Disease and Diabetes
- Cytokine Signaling Pathways and Interactions
- interferon and immune responses
- Renal Diseases and Glomerulopathies
- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
Identifiers and source
- Literature Corpus work
- 8817cf8a-27c9-5b57-a392-042be930672c
- DOI
- 10.21203/rs.2.12276/v3
