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Immune cell infiltration characteristics and related core genes in lupus nephritis: results from bioinformatic analysis

21 Oct 2019

Abstract excerpt

BACKGROUND: Lupus nephritis (LN) is a common complication of systemic lupus erythematosus that presents a high risk of end-stage renal disease. In the present study, we used CIBERSORT and gene set enrichment analysis (GSEA) of gene expression profiles to identify immune cell infiltration characteristics and related core genes in LN. RESULTS: Datasets from the Gene Expression Omnibus, GSE32591 and GSE113342, were...

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PMID: 31638917
DOI: 10.1186/s12865-019-0316-x

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