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Identification of driver genes in lupus nephritis based on comprehensive bioinformatics and machine learning

7 Dec 2023

Abstract excerpt

Background: Lupus nephritis (LN) is a common and severe glomerulonephritis that often occurs as an organ manifestation of systemic lupus erythematosus (SLE). However, the complex pathological mechanisms associated with LN have hindered the progress of targeted therapies. Methods: We analyzed glomerular tissues from 133 patients with LN and 51 normal controls using data obtained from the GEO database....

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PMID: 38130724
DOI: 10.3389/fimmu.2023.1288699

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