Determining IFI44 as a key lupus nephritis’s biomarker through bioinformatics and immunohistochemistry

Abstract excerpt

BACKGROUND: Lupus nephritis (LN) emerges as a severe complication of systemic lupus erythematosus (SLE), significantly affecting patient survival. Despite improvements in treatment reducing LN's morbidity and mortality, existing therapies remain suboptimal, emphasizing the necessity for early detection to improve patient outcomes. METHODS: This study employs bioinformatics and machine learning to identify and...

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