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Article

Polygenic Scores for Type 2 Diabetes Causally Impact Vitamin D Levels Across Diverse Populations

2026-03-09

Abstract excerpt

<h4>Background: </h4> Vitamin D (25(OH)D) deficiency affects over one billion people globally and is associated with type 2 diabetes (T2D) and cardiometabolic diseases. However, causal relationships remain unclear, as vitamin D supplementation have shown limited benefit in reducing T2D risk. Genetic studies have identified variants influencing circulating 25(OH)D levels, but whether genetically determined vitamin...

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Literature Corpus work
87dd1f7b-d42e-53af-b166-55a7b5f9de17
DOI
10.20944/preprints202603.0645.v1
Open publication

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Polygenic Scores for Type 2 Diabetes Causally Impact Vitamin D Levels Across Diverse PopulationsDOI 10.20944/preprints202603.0645.v1
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