Article

Inferring Multi-Organ Genetic Causal Connections using Imaging and Clinical Data through Mendelian Randomization

2023-05-28

Abstract excerpt

Understanding the complex causal relationships among major clinical outcomes and the causal interplay among multiple organs remains a significant challenge. By using imaging phenotypes, we can characterize the functional and structural architecture of major human organs. Mendelian randomization (MR) provides a valuable framework for inferring causality by leveraging genetic variants as instrumental variables. In t...

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Literature Corpus work: 87a868ac-0372-5980-8d95-f67ddf21a4eb
DOI: 10.1101/2023.05.22.23290355

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