Article

Mapping rare protein-coding variants on multi-organ imaging traits

2024-11-18

Abstract excerpt

Human organ structure and function are important endophenotypes for clinical outcomes. Genome-wide association studies (GWAS) have identified numerous common variants associated with phenotypes derived from magnetic resonance imaging (MRI) of the brain and body. However, the role of rare protein-coding variations affecting organ size and function is largely unknown. Here we present an exome-wide association study...

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Literature Corpus work: a407155d-df43-5834-9010-0f93f9129f51
DOI: 10.1101/2024.11.16.24317443

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