Article

Cutting Edge: The Chemokine Receptor CCR8 Is Preferentially Expressed in Th2 But Not Th1 Cells

1998-07-01

Abstract excerpt

Abstract In this paper we report on the cloning and characterization of mouse CCR8. Like its human homologue, it is predominantly expressed in the thymus. In the periphery, murine CCR8 mRNA was found most abundantly expressed in activated Th2-polarized cells and in NK1.1+CD4+ T cells. Human CCR8 is also preferentially expressed in human Th2-polarized cells and clones. This pattern of expression suggests that CCR8...

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Literature Corpus work: 8769e414-f0f1-500a-abdc-3fddd65062f8
DOI: 10.4049/jimmunol.161.2.547

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