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Article

Multifaceted activities of CCR7 regulate T‐cell homeostasis in health and disease

15 Jun 2012

Abstract excerpt

CCR7 is a homeostatically expressed chemokine receptor that is known to regulate the homing of various types of immune cells to primary, secondary, and tertiary lymphoid organs. Recent evidence suggests that, in addition to controlling cell migration, CCR7-mediated signals affect T-cell homeostasis in lymph nodes at various levels and also influence T-cell activation and polarization. In this review, we highlight...

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Share to Chemokine receptors and signaling
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PMID: 22700449
DOI: 10.1002/eji.201242614

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