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Article

ACKR2: An Atypical Chemokine Receptor Regulating Lymphatic Biology

10 Jan 2017

Abstract excerpt

The lymphatic system plays an important role in the induction of the immune response by transporting antigens, inflammatory mediators, and leukocytes from peripheral tissues to draining lymph nodes (LNs). It is emerging that lymphatic endothelial cells (LECs) are playing an active role in this context via the expression of chemokines, inflammatory mediators promoting cell migration, and chemokine receptors....

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PMID: 28123388
DOI: 10.3389/fimmu.2016.00691

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