Article

A Small-Molecule Activity-Based Probe for Monitoring Ubiquitin C-terminal Hydrolase L1 (UCHL1) Activity in Live Cells and Zebrafish Embryos

2019-11-01

Abstract excerpt

<h4>ABSTRACT</h4> Many reagents have been emerged to study the function of specific enzymes in vitro . On the other hand, target specific reagents are scarce or need improvement allowing investigations of the function of individual enzymes in a cellular context. We here report the development of a target-selective fluorescent small-molecule activity-based DUB probe that is active in live cells and whole animals....

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Literature Corpus work: 87431827-08e5-59cc-8561-589da9d29710
DOI: 10.1101/827642

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