Article

Divergent Entry, Convergent Trafficking in Defensin-Mediated Adenovirus Infection

2026-08-13

Abstract excerpt

Human α-defensins can paradoxically inhibit or enhance human adenovirus (HAdV) infection. Defensin-resistant HAdVs exploit α-defensins as molecular bridges to bypass canonical receptors, but whether this mode of entry redirects intracellular trafficking or contributes to defensin resistance remains unknown. Here we systematically compared intracellular trafficking after canonical receptor-mediated versus defensin-...

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Literature Corpus work: 872625bc-522b-54a0-9998-962ef60e2220
DOI: 10.64898/2026.08.13.744638

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