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Article

RNASEK is required for internalization of diverse acid-dependent viruses

8 Jun 2015

Abstract excerpt

Viruses must gain entry into cells to establish infection. In general, viruses enter either at the plasma membrane or from intracellular endosomal compartments. Viruses that use endosomal pathways are dependent on the cellular factors that control this process; however, these genes have proven to be essential for endogenous cargo uptake, and thus are of limited value for therapeutic intervention. The...

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PMID: 26056282
DOI: 10.1073/pnas.1424098112

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