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NOTCH1 fusions in pediatric T-cell lymphoblastic lymphoma: a high-risk subgroup with CCL17 (TARC) levels as diagnostic biomarker

2024-02-02

Abstract excerpt

Twenty percent of children with T-cell lymphoblastic lymphoma (T-LBL) will relapse and have an extremely poor outcome. Currently, we can identify a genetically low-risk subgroup in pediatric T-LBL, yet these high-risk patients who need intensified or alternative treatment options remain undetected. Therefore, there is an urgent need to recognize these high-risk T-LBL patients through identification of molecular ch...

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Identifiers and source

Literature Corpus work
872301d4-5b3b-5f0c-90c9-db092fb2e661
DOI
10.1101/2024.01.31.24301517
Open publication

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NOTCH1 fusions in pediatric T-cell lymphoblastic lymphoma: a high-risk subgroup with CCL17 (TARC) levels as diagnostic biomarkerDOI 10.1101/2024.01.31.24301517
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