Article

Evaluation of efficacy and safety after replacement of methyl hydrogen with Deuterium at 7-position methyl formate of Clopidogrel

2024-01-30

Abstract excerpt

<h4>Background: </h4> and Purpose: As a first-line clinical drug, thienopyridines still have many unsatisfactory aspects, such as the low bioavailability of clopidogrel and the high bleeding risk of prasugrel. Our team synthesized deuterium clopidogrel(the patent has been obtained in China) to mitigate the disadvantages of clopidogrel clinical application, including a slow onset, greater influence of gene polymorp...

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Literature Corpus work: 871cb0c3-b01e-5d4d-83b1-4aa5d44fa56e
DOI: 10.22541/au.170665057.77181915/v1

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