Article

Evaluation of Efficacy and Safety After Replacement of Methyl Hydrogen With Deuterium at 7-position Methyl Formate of Clopidogrel

2021-04-08

Abstract excerpt

<title>Abstract</title> <p>Background and PurposeAs a first-line clinical drug, thienopyridines still have many unsatisfactory aspects, such as the low bioavailability of clopidogrel and the high bleeding risk of prasugrel. Our team synthesized deuterium clopidogrel(the patent has been obtained in China) to alleviate the deficiency of CLP in clinical application, such as a slow onset, greater influence of gene po...

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Literature Corpus work: 2594fcbf-8097-53bd-8f52-c3bd62c458ee
DOI: 10.21203/rs.3.rs-383891/v1

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