Article

Glycine promotes longevity in <i>Caenorhabditis elegans</i> in a methionine cycle-dependent fashion

2018-08-16

Abstract excerpt

The deregulation of metabolism is a hallmark of aging. As such, changes in the expression of metabolic genes and the profiles of amino acid levels are features associated with aging animals. We previously reported that the levels of most amino acids decline with age in Caenorhabditis elegans (C. elegans). Glycine, in contrast, substantially accumulates in aging C. elegans . In this study we show that this is cou...

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Literature Corpus work: 871671f1-4d56-50c3-8b4e-05150ae0860d
DOI: 10.1101/393314

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